Gout and Pseudogout

Gout

Gout (also known as podagra when it involves the big toe) is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis—a red, tender, hot, swollen joint.

gout n : a painful inflammation of the big toe and foot caused by defects in uric acid metabolism resulting in deposits of the acid and its salts in the blood and joints [syn: {gouty arthritis}, {urarthritis}]

Gout \Gout\ (gout), n. [F. goutte a drop, the gout, the disease being considered as a defluxion, fr. L. gutta drop.] [1913 Webster] 1. A drop; a clot or coagulation. [1913 Webster] On thy blade and dudgeon gouts of blood. --Shak. [1913 Webster] 2. (Med.) A constitutional disease, occurring by paroxysms. It consists in an inflammation of the fibrous and ligamentous parts of the joints, and almost always attacks first the great toe, next the smaller joints, after which it may attack the greater articulations. It is attended with various sympathetic phenomena, particularly in the digestive organs. It may also attack internal organs, as the stomach, the intestines, etc. It is an inherited disease of purine metaboism, which causes an increased level of uric acid in the blood, and leads to deposition of crystals of sodium urate in cartilage within joints and in connective tissue. It can be alleviated by a diet low in purines, and is treated by drugs which block formation of uric acid. --Dunglison. [1913 Webster +PJC] 3. A disease of cornstalks. See {Corn fly}, under {Corn}. [1913 Webster] {Gout stones}. See {Chalkstone}, n., 2. [1913 Webster]

GOUT, n. A physician's name for the rheumatism of a rich patient.

Pseudogout

Calcium pyrophosphate dihydrate disease (CPPD) is a rheumatologic disorder with varied symptoms arising due to the accumulation of crystals of calcium pyrophosphate dihydrate in the connective tissues.

Pseudogout is a form of arthritis characterized by sudden, painful swelling in one or more of your joints. These episodes can last for days or weeks. The most commonly affected joint is the knee..

Also called calcium pyrophosphate deposition disease, the common term "pseudogout" was coined for the condition's similarity to gout. Both conditions are caused by crystal deposits within a joint, although the type of crystal differs for each condition.

It isn't clear why crystals form in your joints and cause pseudogout, but the risk increases with age. Treatments can help relieve pain and reduce inflammation.

Data Sources:

  • gout: WordNet (r) 2.0
  • gout: Moby Thesaurus II by Grady Ward, 1.0
  • gout: The Collaborative International Dictionary of English v.0.44
  • gout: The Collaborative International Dictionary of English v.0.44
  • gout: THE DEVIL'S DICTIONARY ((C)1911 Released April 15 1993)
  • pseudogout: mayoclinic http://www.mayoclinic.com/health/pseudogout/DS00717

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